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Biostimulators – building collagen from within

What is it and what is it for?

Biostimulators such as hyperdiluted Radiesse or Sculptra do not simply fill – they prompt the skin to form new collagen of its own. The result is not an instant correction, but a gradual, very natural improvement in skin density, firmness and contour.

How does the treatment work?

The preparation – diluted where appropriate – is placed in the relevant skin layers with a blunt cannula. The treatment takes around 30 minutes.

When will you see the result?

A slight immediate effect is possible, but the actual result develops over weeks to months through collagen formation. It usually lasts 12 to 18 months, often longer. Depending on the starting point, two to three sessions are advisable.

What should you expect afterwards?

What to bear in mind

Who is it not suitable for?

Pregnancy, breastfeeding, infections in the treatment area, certain autoimmune conditions.

Good to know

Both the calcium hydroxylapatite in hyperdiluted Radiesse and the poly-L-lactic acid in Sculptra are body-compatible substances that are fully broken down. What remains is the newly formed collagen of your own – which is why the results look so natural. Radiesse usually shows its effect somewhat earlier, while Sculptra builds structure more slowly but particularly durably.

Dr. Anna Kovács
Written and medically reviewed by Dr. Anna KovácsPhysician for general medicine · Aesthetic treatmentsLast updated: August 2026
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This article provides general information and does not replace a personal medical consultation.
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